I am using an NVD3 line chart.

The chart by default renders legends which are clickable.
I want to build a custom legend using <ul> and <li> elements; clicking these <li>s should toggle their respective line series on the chart.
$(function(){
    nv.addGraph(function() {
        var dayChart = nv.models.lineChart()
            .options({
                transitionDuration: 300,
                useInteractiveGuideline: true,
                interpolate: 'monotone'
            });
        dayChart.xAxis
            .axisLabel('Time')
            .tickValues([0, 1, 2, 3, 4])
            .tickFormat(function(d){
                return ["", "0-6", "6-12", "12-18", "18-24"][d]
            });
        dayChart.yAxis
            .axisLabel('Engagement')
            .tickFormat(function(d) {
                if (d == null) {
                    return 'N/A';
                }
                return d3.format(',d')(d);
            })
        ;
        var data = [
                {"values": [
                    { "x": 0 ,"y": 3 }, { "x": 1 ,"y": 5 }, { "x": 2 ,"y": 2 }, { "x": 3 ,"y": 4 }, { "x": 4 ,"y": 2 }],    "key": "Desktop","color":"#4b758d"
                }
                ,
                {"values": [
                    { "x":  0 ,"y": 1 },    { "x": 1 ,"y": 3 }, { "x": 2 ,"y": 4 }, { "x": 3 ,"y": 3 }],    "key": "Mobile","color":"#99c925"                },
                {"values": [
                    { "x": 0  ,"y": 2 },{"x": 1  ,"y": 4 }, { "x": 2 ,"y": 3 }, { "x": 3 ,"y": 5 }],"key": "Tablet","color":"#f23b71"                }
            ];
        d3.select('#line-chart').append('svg')
            .datum(data)
            .call(dayChart);
        nv.utils.windowResize(dayChart.update);
        return dayChart;
    });
});
Plunker for full demo.
To disable the legend chart.showLedgend(false). More details on how the entire code looks here.
Assuming you have a global instance of your chart, you need to change the state of the chart.
$(document).on('click', '#myButton', function(){
    chart.dispatch.changeState('key');
    chart.update();
});
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