My view hierarchy is this
PhotoDetailViewController.swift
    View
      UIScrollView
        UIImageView
I set this up using storyboard, and add four constraints(top=0, bottom=0, leading=0, tailing=0) to UIScrollView, four constraints(top=0, bottom=0, leading=0, tailing=0) to UIImageView, but there are two error says
"ScrollView has ambiguous scrollable content width"
"ScrollView has ambiguous scrollable content height"
I understand that this is because I haven't set UIScrollView contentSize, but What I trying to do is load photo from PHAsset asynchronously, so I can only get the photo size at run time. So the question is:
1:Given that photo size can only be get at run time, how to solve the "ambiguous scrollable content" error?
2:In which View's life cycle method should I call PHImageManager.requestImageForAsset? because I think I should set UIScrollView contentSize programmatically, but when?
update with PhotoDetailViewController.swift
import UIKit
import Photos
class PhotoDetailViewController : UIViewController {
@IBOutlet weak var scrollView: UIScrollView!
@IBOutlet weak var imageViewBottomConstraint: NSLayoutConstraint!
@IBOutlet weak var imageViewLeadingConstraint: NSLayoutConstraint!
@IBOutlet weak var imageViewTopConstraint: NSLayoutConstraint!
@IBOutlet weak var imageViewTrailingConstraint: NSLayoutConstraint!
var devicePhotosAsset : PHFetchResult!
var index = 0
var photo : UIImage!
var imgManager:PHImageManager!
@IBOutlet weak var imageView : UIImageView!
override func viewWillAppear(animated: Bool) {
    super.viewWillAppear(animated)
}
override func awakeFromNib() {
    self.imgManager = PHImageManager()
}
override func viewDidLoad() {
    super.viewDidLoad()
    self.displayPhoto()
}
override func viewWillLayoutSubviews() {
    super.viewDidLayoutSubviews()
    updateMinZoomScaleForSize()
    updateConstraintsForSize()
}
func displayPhoto () {
    _ = self.imgManager.requestImageForAsset(self.devicePhotosAsset[self.index] as! PHAsset, targetSize: PHImageManagerMaximumSize, contentMode: .AspectFit, options: nil, resultHandler: {(result, info) -> Void in
            NSOperationQueue.mainQueue().addOperationWithBlock(){
                self.imageView.image = result
            }
        })
}
private func targetSize() -> CGSize {
    let scale = UIScreen.mainScreen().scale
    let targetSize = CGSizeMake(CGRectGetWidth(self.imageView.bounds)*scale, CGRectGetHeight(self.imageView.bounds)*scale)
    return targetSize
}
private func updateMinZoomScaleForSize() {
    let size = scrollView.bounds.size
    let widthScale = size.width / imageView.bounds.width
    let heightScale = size.height / imageView.bounds.height
    let minScale = min(widthScale, heightScale)
    scrollView.minimumZoomScale = minScale
    scrollView.zoomScale = minScale
}
func recenterImage(){
    let scrollViewSize = scrollView.bounds.size
    let imageSize = imageView.frame.size
    let horizontalSpace = imageSize.width < scrollViewSize.width ? (scrollViewSize.width - imageSize.width)/2 : 0
    let verticalSpace = imageSize.height < scrollViewSize.height ? (scrollViewSize.height - imageSize.height)/2 : 0
    scrollView.contentInset = UIEdgeInsets(top: verticalSpace, left: horizontalSpace, bottom: verticalSpace, right: horizontalSpace)
}
private func updateConstraintsForSize() {
    let size = scrollView.bounds.size
    let yOffset = max(0, (size.height - imageView.frame.height) / 2)
    imageViewTopConstraint.constant = yOffset
    imageViewBottomConstraint.constant = yOffset
    let xOffset = max(0, (size.width - imageView.frame.width) / 2)
    imageViewLeadingConstraint.constant = xOffset
    imageViewTrailingConstraint.constant = xOffset
    view.layoutIfNeeded()
}
}
extension PhotoDetailViewController: UIScrollViewDelegate {
func viewForZoomingInScrollView(scrollView: UIScrollView) -> UIView? {
    return imageView
}
func scrollViewDidZoom(scrollView: UIScrollView) {
    updateConstraintsForSize()
}
}
Your existing constraints are enough to set the content size, it's just that it's based on the image view intrinsic content size and that doesn't really exist until the image view has an image.
You can add a width and height constraint to the image view with default values and deactivate those constraints when the image is set to the view. Or you could use a placeholder image and avoid those extra constraints because you'd always have an intrinsic content size for the image view.
You should set two more constraint to your imageView. 
Second thing you can put UIView on Scrollview with Constraints like, 
Top,leading,trailing,bottom,Horizontally in container(center x),fixed height).
Then add your imageview to that view. And can change it's constraint after getting image to resize it's height and width.
You can connect outlet of any constraint and can change it's constant programmatically.
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