What CSS toolkit for initial page layout do you prefer? Is there is a solution that would have:
I assume you mean a CSS framework when you say "toolkit".
I've worked with both Blueprint and the 960 Grid System, and they both work well. They are both customizable, and are both modular to some extent.
Overall I found it useful to learn from working with each and seeing what I liked and didn't like, but I've found that there isn't a one-framework-fits-all solution for me. I've created my own base set of resets and styles that I use as a starting point on all my sites and then I customize from there.
The best toolkit is no toolkit. I keep around a few templates (a two column page template, a sidebar template, etc.) and use those as I see fit as well as snippets.
My advice: make your own. We all have fonts, sizes and distances we prefer, and only you can know what those are.
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