https://docs.scipy.org/doc/scipy-0.14.0/reference/generated/scipy.ndimage.morphology.distance_transform_edt.html
I'm having trouble understanding how the Euclidean distance transform function works in Scipy. From what I understand, it is different than the Matlab function (bwdist). As an example, for the input:
[[ 0.  0.  0.  0.  0.]
 [ 0.  1.  0.  0.  0.]
 [ 0.  0.  0.  0.  0.]
 [ 0.  0.  0.  1.  0.]
 [ 0.  0.  0.  0.  0.]]
The scipy.ndimage.distance_transform_edt function returns the same array:
[[ 0.  0.  0.  0.  0.]
 [ 0.  1.  0.  0.  0.]
 [ 0.  0.  0.  0.  0.]
 [ 0.  0.  0.  1.  0.]
 [ 0.  0.  0.  0.  0.]]
But the matlab function returns this:
1.4142    1.0000    1.4142    2.2361    3.1623
1.0000         0    1.0000    2.0000    2.2361
1.4142    1.0000    1.4142    1.0000    1.4142
2.2361    2.0000    1.0000         0    1.0000
3.1623    2.2361    1.4142    1.0000    1.4142
which makes more sense, as it is returning the "distance" to the nearest one.
It is not clear from the docstring, but distance_transform_edt computes the distance from non-zero (i.e. non-background) points to the nearest zero (i.e. background) point.
For example:
In [42]: x
Out[42]: 
array([[0, 0, 0, 0, 0, 1, 1, 1],
       [0, 1, 1, 1, 0, 1, 1, 1],
       [0, 1, 1, 1, 0, 1, 1, 1],
       [0, 0, 1, 1, 0, 0, 0, 1]])
In [43]: np.set_printoptions(precision=3)  # Easier to read the result with fewer digits.
In [44]: distance_transform_edt(x)
Out[44]: 
array([[ 0.   ,  0.   ,  0.   ,  0.   ,  0.   ,  1.   ,  2.   ,  3.   ],
       [ 0.   ,  1.   ,  1.   ,  1.   ,  0.   ,  1.   ,  2.   ,  2.236],
       [ 0.   ,  1.   ,  1.414,  1.   ,  0.   ,  1.   ,  1.   ,  1.414],
       [ 0.   ,  0.   ,  1.   ,  1.   ,  0.   ,  0.   ,  0.   ,  1.   ]])
You can get the equivalent of Matlab's bwdist(a) by applying distance_transform_edt() to np.logical_not(a) (i.e. invert the foreground and background):
In [71]: a
Out[71]: 
array([[ 0.,  0.,  0.,  0.,  0.],
       [ 0.,  1.,  0.,  0.,  0.],
       [ 0.,  0.,  0.,  0.,  0.],
       [ 0.,  0.,  0.,  1.,  0.],
       [ 0.,  0.,  0.,  0.,  0.]])
In [72]: distance_transform_edt(np.logical_not(a))
Out[72]: 
array([[ 1.414,  1.   ,  1.414,  2.236,  3.162],
       [ 1.   ,  0.   ,  1.   ,  2.   ,  2.236],
       [ 1.414,  1.   ,  1.414,  1.   ,  1.414],
       [ 2.236,  2.   ,  1.   ,  0.   ,  1.   ],
       [ 3.162,  2.236,  1.414,  1.   ,  1.414]])
Warren has already explained how distance_transform_edt works.
In your case,you could change sampling units along x and y
ndimage.distance_transform_edt(a)
array([[ 0.,  0.,  0.,  0.,  0.],
       [ 0.,  1.,  0.,  0.,  0.],
       [ 0.,  0.,  0.,  0.,  0.],
       [ 0.,  0.,  0.,  1.,  0.],
       [ 0.,  0.,  0.,  0.,  0.]])
But
>>> ndimage.distance_transform_edt(a, sampling=[2,2])
array([[ 0.,  0.,  0.,  0.,  0.],
       [ 0.,  2.,  0.,  0.,  0.],
       [ 0.,  0.,  0.,  0.,  0.],
       [ 0.,  0.,  0.,  2.,  0.],
       [ 0.,  0.,  0.,  0.,  0.]])
Or
ndimage.distance_transform_edt(a, sampling=[3,3])
array([[ 0.,  0.,  0.,  0.,  0.],
       [ 0.,  3.,  0.,  0.,  0.],
       [ 0.,  0.,  0.,  0.,  0.],
       [ 0.,  0.,  0.,  3.,  0.],
       [ 0.,  0.,  0.,  0.,  0.]])
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